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Epigenetic factors such as the histone demethylase KDM6B, the transcription co-factor and chromatin remodeler Zmiz1, and the MSNP1AS long non-coding RNA (lncRNA) have been reported to modulate mTOR activity

Dose-dependent reductions in lesion volume, weight, and vascularization have also been observed (94, 117)

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[DOI] [PubMed] [Google Scholar] 448.Weik M., Bergs J., Raves M., Gros P., McSweeney S., Silman I., Sussman J., Houe-Levin C., Ravelli R

Besides, the transcriptional levels of ACSL1 can be regulated by super-enhancers (SEs) formed by bromodomain-containing protein 4 (BRD4) and high mobility group box 2 (HMGB2) [124]