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32 As 2-chloroacetamide serves as the electrophile for compounds 69 , it would be interesting to incorporate the N -carbamoyl-2-chloroacetamide moiety in the design of future NNMT covalent inhibitors (Fig
The study addressed two questions: whether the fragment retained activity when delivered enterally rather than parenterally, and whether the effects observed in rodent models translated to human adipose tissue at the cellular level
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