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Objective methods for sleep disorders assessment in cirrhosis include the polysomnography test which stands as the gold standard for diagnosing sleep disturbances, but its practicality is hindered by high costs and patient compliance challenges

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[DOI] [PubMed] [Google Scholar] 249.Archavachotikul K, et al

These alterations may signify the progressive deterioration of these metabolic pathways, possibly contributing to drug dependence following repeated cycles of drug reward, withdrawal, and relapse

10.1038/383710a0 [DOI] [PubMed] [Google Scholar] Dumont M., Kipiani K., Yu F., Wille E., Katz M., Calingasan N