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Three PALS experienced motor improvements, one pilot trial showed some benefit, and defective preclinical studies showed benefits [199]

Promising in vivo anti-tumor efficacy with curative potential was demonstrated in an aggressive pancreas cancer model

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Because this recognition site is normally not saturated 133 , an increase in extracellular glycine can potentiate impulse-dependent NMDA receptor activation, which might be the underlying mechanism for seizure generation in this condition

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