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The structural binding information can be used to gain insight into ligand binding driving target selectivity and/or reactivity [109,110,111,112] and can be combined with (covalent) docking studies [44,113,114,115] to aid the structure-based design of covalent ligands with improved potency and/or selectivity [22,45,116,117,118,119]

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Once reconstituted with bacteriostatic water, the solution is generally stored refrigerated (2-8C) and used within the window supported by internal stability testing

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