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This suggests that metabolic dysregulation of platelet mitochondria in hyperglycemia may produce exaggerated Ca 2+ mobilization and amplified downstream signaling by lowering the receptor threshold, leading to a prothrombotic state (Siewiera et al., 2022)

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Peptide therapy has recently gone mainstream thanks to popular peptides like semaglutide (Ozempic) and tirzepatide (Mounjaro)

In the context of pyroptosis, ROS play roles in the activation of the NLRP3 inflammasome and caspases (Fig
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