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NADPH oxidase inhibition of S17834 was suggested from the observation that it prevented superoxide formation in human umbilical vein endothelial cells (HUVECs)

This linkage occurs via a characteristic tetrasaccharide bridge (GlcA1-3Gal1-3Gal1-4Xyl1-O-Ser)

ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB