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For analysis of genes expressed, TaqMan probes for human IFNG , IFITM3 , IFI27 , IFI44L , IFIT1 , MX1 , ISG15 , MX2 , RSAD2 and SIGLEC1 , mouse Ndusf8 , Sdha , Sdhb , Sdhc , Txnrd1 , Got1 , Arg1 , Tgfb1 , Ccl2 , Ccl3 , Fn1 , Mmp2 and Mmp12 or viral N1 and N2 (SARS-CoV-2) (IDT) were used

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This may be because IDH mutations affect cellular metabolism and antioxidant capacity, thereby altering the regulatory mechanisms and functions of SLC7A11

With NAD levels declining as we age, its important to increase your NAD levels to allow your cells to regenerate and activate the necessary enzymes to prevent any further DNA damage