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In terms of food and beverage interactions, Linzess and coffee together can increase the risk of diarrhea

The fact that NBDHEX is active in cell lines from various cancers, including leukemia, melanoma, osteosarcoma, and small-cell lung cancers, suggests it may be broadly applicable [161]

It also binds to receptors on the pituitary gland, stimulating GH release and boosting IGF-1 production

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Cells (2022) 11(9):1413
