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However, science is particularly interested in it because of its many physiological, endocrine and modulatory effects, such as its ability to alter corticotropin levels, inhibit somatostatin secretion, normalize blood pressure, reduce stress, influence sleep rhythms, or chronic pain perception

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For example, altering the levels of SAM and SAH using 3DAZ, an inhibitor decreases the cellular SAM: SAH ratio, reduces histone methylation of key genes in lipopolysaccharide (LPS)-stimulated macrophages (34)

[Study on the effect of theaflavins on the adhesion between monocyte and endothelial cells]