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The most commonly reported side effects were mild and included headache, minor gastrointestinal disturbances (flatulence, mild diarrhea at high doses), upper respiratory symptoms, and mild injection site reactions
The addition of L-Carnitine may help boost energy and make treatment more comfortable

The risks associated with vitamin B12 deficiency

Barbour LA, Mizanoor Rahman S, Gurevich I, Leitner JW, Fischer SJ, Roper MD, Knotts TA, Vo Y, McCurdy CE, Yakar S, Leroith D, Kahn CR, Cantley LC, Friedman JE, Draznin B

Under cobalamin deficiency, non-regenerative anemia, leukopenia, hypoglycemia, and hyperammonemia seem to be the most frequent hematobiochemical alterations [15,61]