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A recent proteomic study suggested altered mitochondrial function in the cerebrovasculature isolated from deceased cognitively healthy E4 carriers compared to non-E4 carriers, indicating that cerebrovascular bioenergetics may indeed be altered in cognitively healthy E4 carriers (Ojo et al., 2021)

Its important to understand that this medication is not only effective when taken as a supplement by those with heart disease, but it also will help cardiologists determine more individualized treatment strategies for patients who might benefit from it

doi: 10.1093/geronj/23.4.476

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Agrawal A, et al