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The 15-Lipoxygenase-1 Product 13-S-Hydroxyoctadecadienoic Acid down-Regulates PPAR- to Induce Apoptosis in Colorectal Cancer Cells

Dalvit, C., Shapiro, G., Bhlen, J.-M

It also downregulated NRF2 transcriptional activity, decreased the expression of downstream targets such as NQO1, GCLC, GCLM, AKR1C2, and UGT1A6, and inhibited the growth of human lung cancer cells