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They stated that proparacaine inhibited the GR enzyme at high concentrations [29]

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This consequently enhanced methylation of specific colonic epithelial genes (Dpep3, Gstm6, Slc27a2, Col11a2, Sycp2, SNORA22, Tnni1, Gpnmb, Mypn and Acsl6) and suppressed their expression ( 3.3.7 Correlation between gut microbiota and biochemical indicators Based on gut microbiota with reported relative abundance changes in at least two studies, we systematically analyzed their associations with RA-related parameters, inflammatory cytokines, bone quality, and SCFAs

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