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FTY720 (fingolimod, GilenyaR, 2-amino-2[2-(4-octylphenyl)ethyl]-1,3-propanediol) is a structural analogue of S1P derived from myriocin, which acts as a pro-drug that must be phosphorylated by SK2 to be transformed into the active metabolite fingolimod-P

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Both promote angiogenesis through different pathways, potentially creating additive vascular support

As described before, it is a novel method that has passed all the method validation steps and can be widely used to analysis vitamin B 12 in mixed parenteral dosage forms in pharmaceutical industries