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4.1 Imbalance of the oxidative-antioxidant system: multi-source generation and collapse of defense barriers In the pathological microenvironment of CP, the formation of oxidative stress stems from the dual pathological mechanisms of enhanced attack and failed defense, which jointly drive the deterioration of the microenvironment

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Abnormal regulation of this pathway can lead to abnormal melanocyte activity, potentially inducing pigmentation disorders such as melasma [59]

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Int J Mol Sci 21:3688

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10.1002/ajmg.a.32589 102 WuJ.JiangZ.HuangX.LuoZ.PengH

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