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Description
2019;66:e27747
Cigarette smoking and liver diseases
An anatomical CT approach
For example, deletion of hepatic Hmgcs2 using antisense oligonucleotides resulted in a significant increase in hepatic neutral lipid accumulation following regular chow and high-fat feeding conditions in both neonates and adult mice ( hmgcs2 results in a massive deposition of hepatic triglycerides in neonates ( Srebp1 , Chrebp1 , and Scd2 (Fabbrini et al., 2008
However, oral forms are limited by reduced absorption and the need for higher doses, which may lead to inconsistent results
