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There are many symptoms of a Vitamin B12 deficiency to look out for: fatigue and general weakness shortness of breath dizziness or light-headedness brain fog numbness or tingling tongue swelling bloating and/or diarrhea The methylation cycle provides other benefits tooespecially when it comes to pregnancy

([PubMed][1]) 2

Crit Rev Food Sci Nutr 63(19):39803993

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While the exact cause for pernicious anaemia is currently not known, it tends to be more common in women around the age of 60