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UK guidance recommends fasting plasma glucose or OGTT when HbA1c reliability is in doubt

As we age, our natural metabolism slows down, our hormone production declines, and our body becomes incredibly efficient at holding onto energy (fat) for perceived future emergencies

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Per FDA guidance, GLP-1-based medications are generally approved for adults with a BMI over 30, or over 27 with a qualifying health condition such as type 2 diabetes, high blood pressure, or high cholesterol