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The COXs, which generate prostanoids, i.e., prostaglandins (PGs) and thromboxane A 2 (TXA 2 ), were the first enzymes reported to metabolize AA

Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs

FEBS J (2022) 289:196883

Another study demonstrated that blocking CTLA-4mediated signaling during immunization with cryptococcal antigens or during active infection leads to enhanced cell-mediated immunity (CMI), as evidenced by increased anticryptococcal delayed-type hypersensitivity (DTH) responses (Nichols et al., 2002)

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