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Abstract Background Maternal nutrition during critical developmental windows is increasingly recognised as a key determinant of offspring health, a concept central to the developmental origins of health and disease paradigm

Pickart's group showed it attracted immune cells and endothelial cells to wound sites, stimulated nerve outgrowth, and increased the production of vascular endothelial growth factor (VEGF), which promotes new blood vessel formation

For example, focused ultrasound (FUS), a non-invasive technique that briefly opens the BBB in combination with microbubbles, has been used for brain delivery of antibodies, nano-agents, and growth factors (Wang et al., 2022)

GH was also found to promote an increase in mitochondrial oxidative capacity and abundance of several mitochondrial genes when acutely administered (209) while exogenous administration of IGF-1 was associated with a reduced susceptibility of dystrophic muscles to contraction-induced injury (210)