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Determination of SOD activity The total activity of SOD was measured in the supernatant of heart tissue homogenate by the Cayman Chemical SOD Assay kit (USA) which utilizes a tetrazolium salt to detect the generated superoxide radicals by measuring the absorbance at 420 nm

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murinus ) or their beneficial metabolites (e.g., capsiate, CAT) can exert protective effects by inducing IL-10 secretion[30] or upregulating glutathione peroxidase 4 (GPX4) to inhibit ferroptosis[21]

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(Lond.) 11 , 907919 (2016)

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