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In the clinic, coral is also used in various compound preparations, such as Ershiwuwei Shanhu pills and Shanhu Qishiwei pills, which can restore nerve function and relieve pain

G-CIMP + tumors, which frequently harbor IDH1 mutations, align with a proneural gene expression profile and are diagnosed at a younger age, whereas G-CIMP tumors, including most primary GBMs, exhibit a more aggressive phenotype

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Deugnier Y, Bardou-Jacquet , Lain F

A mammalian variant of GST, GSTP, plays a major role in cancer- development and potential drug/chemotherapeutic resistance in a majority of tumor cell lines: The inhibition of the pro-apoptotic pathway (JNK pathway) and the overexpression of GSTP in tumor cells lead to escape of apoptosis of the tumor cells mediated by non GSTP- substance-drugs Hayes et al.,1995 Josephy,2010 Hayes et al.,2000 Fraser et al.,2003