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Feeling constantly tired and lethargic can indicate a lack of vitamin B12

The results showed a lower dose was needed with a breath-powered Optinose device to deliver OT across the nose to the brain

Besides, these met with a common requirement for adverse effects (any of the therapeutic interventions have side effects)

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Hsieh M.J., Liu H.T., Wang C.N., Huang H.Y., Lin Y., Ko Y.S., Wang J.S., Chang V.H., Pang J.S

But they're concerning
