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In a randomized, double-blind, placebo-controlled trial, patients with preserved small nerve fiber function as defined by QST had a statistically and clinically significant improvement in pain

Furthermore, other laboratory experiments allow conclusions about other therapeutic effects of the peptide, such as nerve cell regeneration, protective action during drug withdrawal syndrome, and even in the case of seizures occurring with their excessive intake

Patients who are young when first diagnosed
Monitor for Allergic Reactions: Observe for signs of an allergic reaction, such as hives, itching, swelling, or difficulty breathing

The Met-Glu-His-Phe sequence in Semax is extended by adding a Pro-Gly-Pro (PGP) sequence at its C-terminal end