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Pflugers Arch

385 Another novel proteasome inhibitor, CEP-18770, demonstrates superior and more sustained dose-dependent suppression of tumor proteasome activity than Bortezomib in medulloblastoma

In summary, the highly interconnected nature of redox homeostasis and glycolysis in cancer cells provides an opportunity for synthetic lethal drug combinations targeting GSH synthesis and glucose metabolism

(Berlin: Springer) 215233

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