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After just 6 h of ML226 treatment in HeLa cells, we were able to detect changes in lipoylation on ketoacid dehydrogenases, using an antibody that only detects the active, unmodified form of lipoate 16
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These active compounds induce intrinsic apoptosis via loss of mitochondrial m , which activates a caspase cascade [121]
[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Shaw P., Lerch J., Greenstein D., Sharp W., Clasen L., Evans A., Giedd J., Castellanos F.X., Rapoport J
Stimulatory TSH-Receptor Antibodies and Oxidative Stress in Graves Disease
