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Addition of exogenous LPS caused an increase in SPARC, which in turn led to a decrease in the expression of ZO-1 and occluding, and finally a rise in BBB permeability at 24 h in a concentration-dependent manner (Alkabie et al., 2016)

48 , who reported that NAFLD and nonalcoholic steatohepatitis (NASH) patients' livers had significantly greater levels of LPL messenger RNA (mRNA) expression than did healthy subjects' livers

Ma), and revealed the potential intervention mechanisms involved multiple targets (AKT1, IL-6, VEGFA, CASP3, and JUN) and multiple pathways (AGE-RAGE and HIF-1)

Introduction Microplastics (MPs) and nanoplastics (NPs) are products of the degradation of plastic products resulting from industrial and household activities that, by penetrating all levels of the biosphere, are taking on the character of an environmental catastrophe [1,2]

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