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[5] It does not appear to significantly alter glucose tolerance, insulin sensitivity, or IGF-1 levels, though more research is needed to further support these hypotheses

MS pathology is associated with excessive reactive oxygen species (ROS) and generation of reactive nitrogen species (RNS), causing oxidative/nitrosative stress

Immunohistochemical detection of p53 and progerin, were performed on paraffin sections (3 m), and subsequent sections were exposed to horseradish peroxidase (HRP)-antibody colored with DAB, and visualized by microscopy (BX51, Olympus, Japan)

Although molecular docking revealed that atractylon can bind to sirtuin 3, the detailed mechanism by which atractylon controls the expression of sirtuin 3 remains unclear

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