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These findings suggest that grape seed PCs can substantially reduce oxidative stress resulting from UVB exposure while providing protective effects against skin damage caused by UVB radiation ( In conclusion, the aforementioned research indicates that PCs can mitigate oxidative stress associated with aging skin by neutralizing ROS accumulation, suppressing lipid peroxidation caused by ROS, and enhancing overall antioxidant capacity, as shown in Table 2

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These findings characterize the cellular distribution of GPX3 within the STAD immune microenvironment and provide initial insights into its potential regulatory function