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The subsequent Phase IIb OPTIONS trial enrolled 536 subjects over 24 weeks

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Common and Serious Side Effects of Pemetrexed Disodium Like all chemotherapy agents, pemetrexed disodium side effects can range from mild to severe, affecting various body systems

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Proc Natl Acad Sci U S A 1993;90:8088-92

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Potent pro-inflammatory actions of leukemia inhibitory factor in the spinal cord of the adult mouse

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TP73 increases by 938%, while USP29 (which stabilizes p53) increases by 1,056%

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