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IR780-loaded MSNs nanoparticles can accumulate in tumors, destroy mitochondria and inhibit cellular respiration by decomposing H 2 O 2 , resulting in sustained reduction of hypoxia in tumor tissues, thereby enhancing the therapeutic effect of PDT (204)
Additionally, caspase-3 can be activated by caspase-8
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Support materials with very large pores give essentially unhindered diffusion for most solutes, but they also have a smaller surface area per milliliter of bed volume than supports with smaller pores
10.1093/jn/125.6.1401 113
