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BDNF is downregulated in HD brains 10 , reducing TrkB signalling

119 illustrated the surface modification of GO through noncovalent functionalization using porphyrins, specifically TPP(5,10,15,20-tetraphenyl-H21,H23-porphine) and ZnTPP (zinc(II) meso-tetraphenylporphyrin), via a self-assembly process that exploits - stacking and coordination with oxygen functional groups

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These findings indicate that MG exerts a pronounced inhibitory effect on selenoprotein production