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Lall S, Tung LY, Ohlsson C, Jansson JO, Dickson SL

Appl Catalysis B: Environ (2005) 56(1-2):11126

The critical difference from other GHRPs is that ipamorelin achieves maximal GH release at doses that do not significantly activate GHSR on corticotroph cells (which would release ACTH/cortisol) or lactotroph cells (which would release prolactin)

By designing a tissue-specific and inducible silencing sequence in an RNAi vector, some of the off-target effects can be avoided [83]

Immunity 45 , 374388 (2016)
