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Description
His159 serves as proton acceptor, which interacts directly with nitrogen of the peptide bond to be cleaved

signs of an allergy may include rash, hives, itching, or even anaphylaxis (a severe allergic response) in highly sensitive individuals

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Moreover, when induced with lipopolysaccharide (LPS), Nrf2-deficient mice have a more pronounced release of ROS, microglial activation, and neuro-inflammatory response than normal mice (269)