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Ergothionase catalyzes the degradation of ergothioneine to produce TMA and the by-product thiosulfonate (Muramatsu et al., 2013)

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[Google Scholar] 68.Ludwig U., Holzner D., Denzer C., Greinert A., Haenle M.M., Oeztuerk S., Koenig W., Boehm B.O., Mason R.A., Kratzer W., et al

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In a prospective, double-blind, randomized, placebo-controlled trial, a group of patients with MASH received either 1000 IU and 1000 mg of vitamin C and E or a placebo daily for six months
