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2025;20(6), 880-892

Simultaneously, the preservation of SAM levels maintains cellular capacity for critical methylation reactions including histone modifications, DNA methylation, and protein methylation that regulate gene expression and protein function

Using a design of experiments (DOE) framework, we systematically evaluated combinations of extracellular matrix proteins and soluble factors to identify conditions that reduce myofibroblastic marker expression and extracellular matrix production

Clinical trial durations: Most obesity studies used daily dosing for 12 weeks

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