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Ng et al., Journal of Endocrinology found that AOD-9604 stimulates lipolysis and inhibits fat storage without increasing IGF-1 or causing anabolic effects

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Moreover, phospho-BCL-XL (Ser62) stabilizes G2 arrest by binding to and co-localizing with Cdk1 (cdc2) in nucleolar structures to avoid rapid nucleolar disassembly associated with mitosis onset, playing an unexpected role in the G2 phase checkpoint downstream of DNA damage distinct from its anti-apoptotic function 22

doi: 10.1186/s40364-024-00679-6 210 MinguetSMausMVSchamelWW