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It already starts when the body is trying to fight against the harmful irritant. Thus, severe inflammation can trigger body stress, including pain, swelling, chronic fatigue, and discomforts that affect skin vitality (i.e

Consequences of cellular cholesterol accumulation: basic concepts and physiological implications

Cantin AM, Paquette B, Richter M, Larive P: Albumin-mediated regulation of cellular glutathione and nuclear factor kappa B activation

All these models are also helpful to test potential therapeutic strategies for LS, such as gene augmentation therapy or bezafibrate treatment, which promote mitochondrial biogenesis and support neuronal morphogenesis (Lyu et al., 2022)