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ter Horst, K

Carbonyl cyanide m-chlorophenyl hydrazine renders the inner mitochondrial membrane permeable to H+, leading to membrane potential destabilisation on both sides of the inner mitochondrial membrane, and then, via the Pink1-Parkin pathway, which is specific for membrane potential destabilisation, the mitochondria undergo further membrane potential (MMP) hyperpolarisation, which generates ROS

eLife 7:e35987

Immediate improvement with straighter bridge and enhanced contours

1 Introduction Mitochondria are essential intracellular organelles that primarily facilitate energy production and metabolic regulation ( Mitochondria play a particularly critical role in tumorigenesis and progression ( Recent years have witnessed significant advancements in tumor immunotherapy, particularly with the advent of immune checkpoint inhibitors