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Iron overload and impaired iron handling contribute to the dystrophic pathology in models of duchenne muscular dystrophy

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52 KeastD.ArsteinD.HarperW.FryR

A healthy body utilizes an enzyme called glutathione reductase to recycle this oxidized molecule back into its active state, maintaining a delicate, continuous cycle of protection

TDP-43 is usually found in the nucleus, but in many cases of ALS it accumulates in the cytoplasm (TDP-43 proteopathy) (Thakur et al
