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When a mouse carrying a xenograft produced by a mixture of HCTT16 WT and HCT116 p53 -/ p53 - is treated with an anti VEGF antibody an initial shrinkage of the tumour occurs as most of the WT-hypoxia sensitive cells undergo apoptosis
The patient showed a slight decrease in CESD-R-20 scores and a mild reduction in depression symptoms, as well as a decrease in PAS scores with some reduction in anxiety symptoms, but these declines were not statistically significant
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