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10.1053/j.gastro.2007.03.054 115
Tarry stool, also known as melena, is usually caused by bleeding in the upper GI tract
Experimental models suggest TMAO may alter cholesterol metabolism, impair vascular function, and promote inflammation
doi:10.1136/ard-2023-224416
For example, insulin (a globular protein) has a combination of hydrogen bonds and disulfide bonds that cause it to be mostly clumped into a ball shape
