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Most antioxidants including ascorbic acid, uric acid, glutathione, which are hydrophilic and alpha tocopherol (vitamin E) and ubiquinol which are lipophilic belong to this category

Compared to conventional serum biomarkers and medical imaging, examining the KRAS mutation level using genomic and transcriptomic techniques has significantly improved diagnostic sensitivity and specificity, indicating potential clinical application value ( KRAS mutations in the blood circulation was positively associated with poorer prognosis ( KRAS G12V mutations in the circulation of patients with PDAC was associated with a high percentage of circulating Tregs

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Macrez et al., 2016)

This means healing materials, oxygen, nutrients, and growth factors delivered through blood struggle to reach the exact area where damage occurs