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As the sun rises on the new year, usually a time of hope and of refocusing on personal goals, the promise of an end to the pandemic and a return to normalcy seem to be as far away as ever

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Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization

The healthy participant population within the Simcyp simulator was modified to include ~17% intermediate CYP2D6 metabolizers and ~83% extensive CYP2D6 metabolizers based on the urinary log (dextromethorphan/dextrorphan) ratios of the clinical study participants (data not shown)