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These experiments indicated that, in addition to requiring Cys-dependent de novo biosynthesis of GSH for survival (see above), TrxR1/Gsr-null livers require de novo biosynthesis of Cys via transsulfuration, and that they cannot effectively utilize cystine as a hepatic Cys source [107]

Renal clearable nanocarriers: overcoming the physiological barriers for precise drug delivery and clearance

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We considered the role of these secondary GH regulators and clustered them as groups of GHstimulatory neurotransmitters ( Table 1 ), neuropeptides ( Table 2 ) and peripheral factors ( Table 3 ), as well as the inhibitory molecules ( Table 4 )

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