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When combined with semaglutide in CagriSema, results are comparable to Zepbound, though slightly lower in a head-to-head trial

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Additional conditions under the umbrella of congenital IGF-1 deficiencies include a documented case of a 15-year-old boy suffering from severe prenatal and postnatal growth failure, sensorineural deafness and mental retardation due to a homozygous partial deletion of the IGF-I gene [41] as well as IGF1R genes defects [42]