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10.1016/j.rmed.2023.107155 13

One pathway The Nrf2 signalling system, the route through which sulforaphane's research links to glutathione are drawn Much of the research interest centres on the Nrf2 pathway, a signalling system the literature associates with the regulation of antioxidant-related and stress-response genes

doi: 10.1007/s10545-009-9006-9 46 McBeanGJ

A case in point, when 2 different mouse strains were exposed to therapeutic or hepatotoxic doses of APAP, depletion of GSH or APAP protein adduct formation was only detected in the liver but not in the whole brain or individual brain regions, suggesting that there is no evidence for the formation of the reactive metabolite NAPQI in the brain of adult mice [185]

This is because the life cycle of red blood cells is 90 days