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This effect is primarily attributed to methylxanthines, such as theobromine, which induces LES relaxation through a mechanism similar to caffeine (Reference Fredholm190)

When all is said and done, the body may not fully absorb the entire dose, and it can take time to feel the effects

Alarcn-Segovia D, Alarcn-Riquelme ME, Cardiel MH et al (2005) Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort

Heavy metals are naturally occurring elements with a large atomic weight and density of at least 5 times greater than that of water (47)

Neurotrophin-3 and Brain-Derived Neurotrophic Factor Induce Oligodendrocyte Proliferation and Myelination of Regenerating Axons in the Contused Adult Rat Spinal Cord