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Description
When blocking glucose metabolism, tumor cells rapidly adapt to metabolic inhibition by switching energy pathways (e.g., glutaminolysis or fatty acid oxidation), limiting the efficacy of glycolysis inhibitors like 2-DG or HK2-targeting agents [129]

Beyond tissue-based markers, dynamic changes in circulating damage-associated molecular patterns (DAMPs) linked to RCD, such as HMGB1 and cell-free DNA, have emerged as promising non-invasive biomarkers (186188)

Human metabolic phenotype diversity and its association with diet and blood pressure

249 The two classic strains are Streptomyces coelicolor and Streptomyces lividans , followed by several other widely used strains such as Streptomyces albus and Streptomyces avermitilis

Konoplev S, Kornblau SM, Schlette E, Lu H, Thomas DA, Zhang N, Qiu YH, Coombes K, Neeley S, Kantarjian HM, Medeiros LJ, Andreeff M , Konopleva M
